There is no required number of U.S. workers that have to be hired to work in the business, but usually the business should employ at least some employees in the U.S. as reasonably necessary for the business to operate. If no workers are hired, the investment may be considered as a business that is set up only to support the E-2 applicant and his or her family. You do not have to hire the workers immediately, and your 5-year business plan should detail exactly when you plan to hire the employees.